Viral Vitalism

Creatine memory meta-analysis / Meta-analysis

Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials

A memory-specific signal is more defensible than a broad claim that creatine upgrades all cognition.

Early evidenceCreatine

Plain-English Summary

A memory-specific signal is more defensible than a broad claim that creatine upgrades all cognition. Potential effects may be more relevant in specific populations than as a universal brain supplement.

VV Study Evidence Matrix v1.0

VV Evidence Utility Score

A bounded score for how useful this study is in public explanation, based on evidence tier, design, applicability, endpoint relevance, limitations, safety signals, and publication/source strength.

71/100

Useful Public Evidence

Evidence tier
78/100, weight 18%
Design strength
83/100, weight 18%
Applicability
72/100, weight 16%
Endpoint relevance
58/100, weight 16%
Limitations transparency
60/100, weight 12%
Safety signal usefulness
57/100, weight 10%
Publication/source strength
88/100, weight 10%

Useful for context, but limited by safety signal usefulness, endpoint relevance, limitations transparency.

How the study framework works ->

Key Findings

  • A memory-specific signal is more defensible than a broad claim that creatine upgrades all cognition.
  • Potential effects may be more relevant in specific populations than as a universal brain supplement.

Limitations

  • Heterogeneity in populations, dose, duration, and memory tests.
  • Does not establish disease-prevention or lifespan benefit.

Why It Matters

This record anchors the creatine-brain-muscle-longevity-claims Signal to an exact source URL, study design, population, and endpoint.

Viral Vitalism Verdict

Useful evidence when kept inside its population, endpoint, and design limits.

Sources

  1. Creatine supplementation and memory meta-analysis - Nutrition Reviews

Signal cards

Used in signals

Signal coverage connected to this study through explicit study links, canonical source refs, or evidence visualizations.

NutritionHuman trialCreatine

Creatine Beyond Muscle: Cheap Supplement or Overextended Brain Hack?

Creatine is one of the rare supplements where the baseline evidence is not flimsy. That makes the overclaim risk more interesting: strong sports-nutrition evidence is now being stretched into cognition, depression, aging, women’s health, sleep deprivation, and neuroprotection.

VV Signal Score

78

Promising signal

Sources
7
Studies
6
Claims
4
Creatine cognition reviewCreatine health and disease reviewCreatine memory meta-analysis
15 min readRead Signal->

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