- Source type
- Meta-analysis
- Access type
- Publisher
- Publisher
- JAMA Pediatrics
- Date
- 2025
- Added
- 2026-07-01
Trust profile
VV Source Trust Matrix v1.0
VV Source Trust Matrix v1.0 asks whether this source is trustworthy for the claim lane being used, not whether every possible claim from it is equally strong.
88
Peer-reviewed research publisher
- Publisher type
- Peer-reviewed journal
- Bias profile
- Moderate
This source is strongest for clinical outcomes and mechanism and weaker for regulatory status and trial discovery.
VV Source Fit Score 1.0
Fit by use case
Fit scores are role-specific. A source can be excellent for one claim lane and weak for another.
- Regulatory status
- 65/100
- Context Source
- Clinical outcomes
- 92/100
- Primary Anchor
- Mechanism
- 90/100
- Primary Anchor
- Safety
- 86/100
- Strong Support
- Consumer context
- 72/100
- Context Source
- Trial discovery
- 65/100
- Context Source
Best used for
- Primary studies
- Systematic reviews
- Mechanistic research
Weak for
- Regulatory status
- Universal consumer recommendations
Used in Viral Vitalism
Fluoride: Cavity Shield or IQ Risk?
Roles: Supporting evidence
Show section-level references
Fluoride exposure and children's IQ scores: systematic review and meta-analysis
Roles: Supporting evidence
Show section-level references
Claim ledger
Claims supported
Reviewed claim cards that cite this source in the evidence graph.
fluoride: The strongest fluoride neurodevelopment concern is dose-sensitive and concentrated
The strongest fluoride neurodevelopment concern is dose-sensitive and concentrated around higher total exposure, not a blanket proof that every fluoridated water system lowers IQ.
fluoride: Evidence is not strong enough to conclude that the
Evidence is not strong enough to conclude that the U.S. recommended community-water level around 0.7 mg/L causes lower IQ, even though higher-exposure findings justify scrutiny.
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Related sources
UCSF Clinical Trials: NGN-401 Rett syndrome study
Canonicalized from June 30, 2026 rapid-brief batch.
- Trust score
- 84
- Publisher
- UCSF Clinical Trials
- Access
- Publisher
- Usage
- 1 connection
NTP monograph on fluoride exposure, neurodevelopment, and cognition
Government research synthesis source for fluoride neurodevelopment concerns at higher exposure levels, used to keep IQ claims dose-specific and separate from standard 0.7 mg/L fluoridation claims.
- Trust score
- 91
- Publisher
- National Toxicology Program
- Access
- Official
- Usage
- 11 connections
CDC: About Community Water Fluoridation
Government public-health source for community water fluoridation benefits, recommended concentration context, dental equity framing, and CDC’s current population-level cavity-prevention position.
- Trust score
- 91
- Publisher
- Centers for Disease Control and Prevention
- Access
- Official
- Usage
- 13 connections
FDA: North American coral snake antivenin expiration-date extension
Primary FDA safety and availability source for coral snake antivenin Lot CL6814 extension.
- Trust score
- 94
- Publisher
- U.S. Food and Drug Administration
- Access
- Official
- Usage
- 1 connection
Ten great public health achievements: fluoridation of drinking water
Government historical public-health context source used to document why fluoridation became institutionally framed as a major prevention success; not used to settle current dose or neurodevelopment disputes.
- Trust score
- 91
- Publisher
- MMWR
- Access
- Official
- Usage
- 2 connections
U.S. Public Health Service recommendation for fluoride concentration in drinking water
Government recommendation source for the 0.7 mg/L U.S. fluoride concentration target, used as the dose boundary separating standard fluoridation from higher-exposure findings.
- Trust score
- 91
- Publisher
- Public Health Reports
- Indexed by
- PubMed
- Access
- Abstract/index
- Usage
- 6 connections