- Source type
- Study
- Access type
- Publisher
- Publisher
- Cell Metabolism
- Date
- 2019-07-02
- Added
- 2026-06-27
Trust profile
88
Peer-reviewed research publisher
- Publisher type
- Peer-reviewed journal
- Bias profile
- Moderate
Best used for
- Primary studies
- Systematic reviews
- Mechanistic research
Weak for
- Regulatory status
- Universal consumer recommendations
Used in Viral Vitalism
Calories Are the Accounting System, Not the Whole Metabolic Story
Roles: Primary source
Show section-level references
Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain
Roles: Primary source
Show section-level references
Claims supported
- Calories describe the accounting of tissue-energy change, but they do not explain all biological friction around appetite, expenditure, adaptation, food environment, hormones, sleep, lean mass, and maintenance.
- Ultra-processed diets can increase spontaneous calorie intake and weight gain under controlled inpatient conditions, even when presented diets are broadly matched for macronutrients, sugar, sodium, and fiber.
Related studies
Related sources
SURMOUNT-MMO trial registry: tirzepatide and morbidity/mortality in obesity
ClinicalTrials.gov / Lilly Trial Registry used across the Viral Vitalism evidence library.
- Trust score
- 84
- Publisher
- ClinicalTrials.gov / Lilly Trial Registry
- Access
- Publisher
- Usage
- 3 connections
CDC: Steps for Losing Weight
Centers for Disease Control and Prevention used across the Viral Vitalism evidence library.
- Trust score
- 91
- Publisher
- Centers for Disease Control and Prevention
- Access
- Official
- Usage
- 7 connections
NIDDK: Choosing a Safe & Successful Weight-loss Program
National Institute of Diabetes and Digestive and Kidney Diseases used across the Viral Vitalism evidence library.
- Trust score
- 91
- Publisher
- National Institute of Diabetes and Digestive and Kidney Diseases
- Access
- Official
- Usage
- 9 connections
Daily Value on the Nutrition and Supplement Facts Labels
Use for U.S. Nutrition Facts and Supplement Facts Daily Value context when discussing fiber, saturated fat, sodium, calcium, potassium, iodine, magnesium, and vitamins.
- Trust score
- 94
- Publisher
- U.S. Food and Drug Administration
- Access
- Official
- Usage
- 4 connections
Dietary Guidelines for Americans, 2025–2030
Use for current U.S. dietary-guidance context and contrast with zero-plant eating patterns.
- Trust score
- 91
- Publisher
- U.S. Department of Health and Human Services / U.S. Department of Agriculture
- Access
- Official
- Usage
- 3 connections
FDA approves Wegovy to reduce risk of serious heart problems in adults with obesity or overweight and cardiovascular disease
U.S. Food and Drug Administration used across the Viral Vitalism evidence library.
- Trust score
- 94
- Publisher
- U.S. Food and Drug Administration
- Access
- Official
- Usage
- 6 connections
