ReviewGovernment health research
- Source type
- Review
- Access type
- Full text
- Publisher
- PubMed Central
- Date
- 2025
- Added
- 2026-06-19
Trust profile
91
Government health research
- Publisher type
- Government research
- Bias profile
- Low
Best used for
- Research synthesis
- Public-health context
- Safety resources
Weak for
- Primary endpoint extraction when a study is available
Used in Viral Vitalism
Supporting evidencesignal8 references
GLP-1s, Dopamine, and Addiction: The Substance Use Signal
Roles: Supporting evidence
Supporting evidencestudy1 reference
GLP-1 analogues in the neurobiology of addiction
Roles: Supporting evidence
Show section-level references
Claims supported
- GLP-1 signaling may modulate reward-related circuits, but GLP-1 medicines are not dopamine blockers and mechanistic plausibility is not proof of clinical benefit.
Related studies
Related sources
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Clinical Trial of Rybelsus (Semaglutide) Among Adults With Alcohol Use Disorder
Trial registry for oral semaglutide among adults with AUD.
- Trust score
- 84
- Publisher
- ClinicalTrials.gov
- Access
- Official
- Usage
- 1 connection
Trial registryClinical trial registry
Does Semaglutide Reduce Alcohol Intake
Trial registry for semaglutide and alcohol intake.
- Trust score
- 84
- Publisher
- ClinicalTrials.gov
- Access
- Official
- Usage
- 1 connection
Trial registryClinical trial registry
Effects of Semaglutide on Nicotine Intake
Trial registry for semaglutide and nicotine intake.
- Trust score
- 84
- Publisher
- ClinicalTrials.gov
- Access
- Official
- Usage
- 2 connections
Trial registryClinical trial registry
ESSENCE clinical trial registry
ClinicalTrials.gov used across the Viral Vitalism evidence library.
- Trust score
- 84
- Publisher
- ClinicalTrials.gov
- Access
- Official
- Usage
- 3 connections
Trial registryGovernment health research
ESSENCE phase 3 trial design for semaglutide in MASH
PubMed used across the Viral Vitalism evidence library.
- Trust score
- 91
- Publisher
- PubMed
- Indexed by
- PubMed
- Access
- Abstract/index
- Usage
- 2 connections
Trial registryClinical trial registry
GLP-1R Agonist Treatment for Opioid Use Disorder
Trial registry testing whether semaglutide can reduce illicit opioid use in adults in outpatient OUD treatment.
- Trust score
- 84
- Publisher
- ClinicalTrials.gov
- Access
- Official
- Usage
- 1 connection
Topic tags
glp-1dopaminereward-circuitryaddictionreview